ELASTOSIS PERFORANS SERPIGINOSA PDF

Elastosis perforans serpiginosa (EPS) is a rare disorder classified as a primary perforating dermatosis. That group of diseases also includes. Four types of elastosis perforans serpiginosa (EPS) have been described in literature: 1) idiopathic EPS, 2) reactive perforating elastosis. Elastosis perforans serpiginosa (EPS) is a rare dermatologic condition where connective and elastic tissues are viewed as foreign objects and subsequently.

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Patient 1 after 2 months of treatment with 0. Saxena M, Tope WD. A year-old healthy man visited Gangnam Severance Hospital with hyperkeratotic papules on his anterior neck. Imiquimod therapy for elastosis perforans serpiginosa. Our website uses cookies to enhance your experience. Histopathology of the Skin.

Elastosis Perforans Serpiginosa

The fibers in the papillary layer are thickened, arranged vertically and penetrate into the skin, where they form characteristic narrow tunnels with a right, wave or spiral ssrpiginosa. Tazarotene may have comedolytic properties that allow for serpigniosa unplugging of transepidermal pores in this disease. The lesions were perforana into an annular arrangement, spreading outwards and leaving erythematous macule in the center Figures 1 A, B.

The diagnosis of EPS should not be based solely on the dermatological examination and evaluation of EPS-specific skin lesions, but rather on the histological assessment of biopsy of the affected skin [ 1 ].

Treatment with topical tretinoin including topical 0. A year-old woman was referred to our institution for evaluation of a prutitic “nonhealing scar” that had been present on the posterolateral aspect of the left serpigonosa of her neck for 1 year.

Report of a case and review of the literature. J Am Acad Dermatol. Based on these findings, a diagnosis of elastosis perforans serpisinosa was made. The middle of each lesion is umbilicated from which the material containing damaged elastic fibers is extruded [ 12 ]. By using this site, you agree to the Terms of Use and Privacy Policy.

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Oxford Textbook of Medicine.

Elastosis perforans serpiginosa and associated disorders. Related articles D-penicillamine elastosis perforans serpiginosa lumpy-bumpy elasttosis fibers. The patient was treated unsuccessfully with cryotherapy approximately 6 times; high-potency topical corticosteroids, including clobetasol and halobetasol, for 6 weeks; topical 0. Burkhart and Burkhart 5 reported tazarotene’s effectiveness in treating a patient with Darier disease who had responded poorly to other agents.

The disease prevalence has not been clearly specified so far but this is not a condition commonly found in routine clinical practice. Patient 1 has tried to taper her usage of tazarotene but notices flares on discontinuation.

YAG laser, are reported to induce complete clearing of EPS lesions, but another report showed only mild improvement of EPS lesions and subtle atrophic scarring after carbon dioxide laser treatment Keloid Hypertrophic scar Cutis verticis gyrata.

Cutaneous lupus erythematosus chronic: All five Korean patients including our patient presented with eerpiginosa lesions on the neck, the most frequently affected EPS site. Author information Article notes Copyright and License information Disclaimer. Both patients agreed and began using 0.

National Center for Biotechnology InformationU. A list of possible co-morbidities of EPS is shown in Table 1 [ 3 — 6 ].

Elastosis perforans serpiginosa: a review of the literature and our own experience

Moreover, even though transepidermal elimination can occur in any of the three other perforating diseases, the elastic tissue changes present in EPS are virtually pathognomonic. Please review our privacy policy. A case of elastosis perforans serpiginosa. Over time, the skin lesions had elasgosis peripherally with some central clearing. In cases of penicillamine-induced EPS, calcification can be observed between the collagen fibers [ 1 — 4 ]. The second form of the disease is a drug-induced one, which is caused by treatment with D-penicillamine.

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The dermatological perdorans revealed some reduced psoriatic plaques on the skin of the elbows and scalp. Pertorans EPS, protrusions of altered elastic fibers and other connective tissue material through the papillary layer and epidermis called transepithelial elimination clinically manifest as small papules arranged in an annular pattern [ 12 ].

In addition, the patient was suffering from hypothyroidism, tetralogy of Fallot and bilateral congenital dislocation of setpiginosa hip joints. Elastic fibers perforate through the epidermis in patients with EPS. A case of elastosis perforans serpiginosa associated with pseudoxanthoma elasticum. Published by Wolters Kluwer – Medknow.

Partially the parakeratotic keratin plug contains an addition of basophilic masses and crumbled nuclei of inflammatory cells. The “lumpy-bumpy” elastic fiber. YAG laser and pulsed dye lasers.

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Elastosis perforans serpiginosa EPS is a rare skin condition characterized by hyperkeratotic papules, transepidermal elimination of abnormal elastic fibers, and focal dermal elastosis.

Perforaans papules coalescing to form serpiginous plaques with central clearing, atrophy and serpigionsa hyperkeratotic rim over sides of the neck Click here to view.

Self-skin examination New smartphone apps to check your skin Learn more Sponsored content. Online since 15 th March ‘ After obtaining the result of the histopathological examination, the nature of the disease, possibilities as well as the effectiveness and purpose of the treatment were explained to the parents. Tazarotene is an effective therapy for elastosis perforans serpiginosa.